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Valsartil 160/12.5mg Tablet 10pcs
Valsartan + Hydrochlorothiazides help to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes, and kidney failure.
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✅ Description:
- Controls high blood pressure, reducing the risk of heart attacks, strokes, and kidney failure.
- Administration: This can be taken with or without food. Take regularly at the same time each day.
- Dosage: Determined by your condition and response to treatment. Follow your doctor's instructions.
- Duration: Continue taking until advised otherwise by your doctor, even if you feel well.
- Diuretic Effect: Increases urination. Avoid taking close to bedtime to prevent disturbance.
- Consistency: Regular use is crucial for optimal results, as high blood pressure often has no symptoms.
- Side Effects: Commonly include dizziness, tiredness, nausea, diarrhea, headache, and decreased blood pressure.
- Frequent Urination: Not a side effect but a desired effect to help control blood pressure.
- Hydrochlorothiazide may increase eye pressure, leading to permanent damage if untreated.
- Avoid Potassium Supplements unless prescribed by your doctor.
- Pregnancy/Breastfeeding: Not recommended without consulting your doctor.
- Pre-existing Conditions: Seek medical advice if you have kidney or liver disease, heart issues, or diabetes.
- Alcohol: Consumption can further lower blood pressure and may amplify side effects.
Safety Advices
Alcohol
UNSAFE
It is unsafe to consume alcohol with Valsartil 160/12.5.
Pregnancy
CONSULT YOUR DOCTOR
Valsartil 160/12.5 is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Valsartil 160/12.5 is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Valsartil 160/12.5 may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Valsartil 160/12.5 should be used with caution in patients with severe kidney disease. A dose adjustment of Valsartil 160/12.5 may be needed. Please consult your doctor. Use of Valsartil 160/12.5 is not recommended in patients with severe kidney disease.
Liver
SAFE IF PRESCRIBED
Valsartil 160/12.5 should be used with caution in patients with liver disease. Dose adjustment of Valsartil 160/12.5 may be needed. Please consult your doctor.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Valsartil 160/12.5mg Tablet
- Hypertension (high blood pressure)
✔️ How does Valsartil 160/12.5mg Tablet work?
- Valsartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently.
- Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.
✔️ Side Effects of Valsartil 160/12.5mg Tablet
- Common: Headache, dizziness, fatigue, abdominal pain, cough, diarrhea, nausea.
- Others: Hyperkalemia, reduced renal function, allergic reactions, dyspnea, constipation, back pain, muscle cramps, rash, anxiety, insomnia, vertigo, hypotension.
✔️ Quick Suggestions:
- You have been prescribed Valsartil 160/12.5 for the treatment of high blood pressure.
- It can be taken with or without food.
- Valsartil 160/12.5 may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth, or muscle weakness.
- It may cause dizziness. Get up slowly when rising from a sitting or lying position.
- Use of Valsartil 160/12.5 during pregnancy or breastfeeding is unsafe.
- It may also decrease the risk of stroke and heart attacks.
✔️ Indication of Valsartil 160/12.5mg Tablet
- Treatment of hypertension (high blood pressure).
✔️ Pharmacology
- Valsartan: An angiotensin II receptor blocker (ARB) that prevents angiotensin II from binding to its receptors, causing blood vessels to relax and lower blood pressure.
- Mechanism: Blocks angiotensin II AT1 receptors, leading to vasodilation.
- Selectivity: 20,000 times more affinity for AT1 receptors than AT2 receptors.
- Hydrochlorothiazide: A thiazide diuretic that increases the excretion of sodium and chloride, reducing plasma volume and consequently lowering blood pressure.
- Mechanism: Increases renal excretion of sodium and chloride, leading to decreased plasma volume and lower blood pressure.
- Effects: Increases plasma renin, aldosterone secretion, and urinary potassium loss, which can be counteracted by ARBs.
✔️ Dosage & Administration of Valsartil 160/12.5mg Tablet
- For Hypertension: Patients not controlled with monotherapy should switch to Valsartil Plus once daily.
- Max Dose: Valsartan 320 mg and Hydrochlorothiazide 25 mg.
- Elderly: No dosage adjustment is needed.
- Pediatric Use: Not established.
- Renal Impairment: Use regular regimens if creatinine clearance is>30 ml/min; use loop diuretics if clearance is lower.
- Hepatic Impairment: Use caution and monitor closely.
✔️ Interaction
Valsartan:
- Diuretics: These may cause excessive blood pressure reduction.
- Potassium Supplements: Can lead to hyperkalemia.
- Lithium Salts: Monitor serum lithium levels closely.
- Others: Warfarin, Digoxin.
Hydrochlorothiazide:
- Alcohol/Barbiturates/Narcotics: May enhance antihypertensive effects.
- Antidiabetics: Dosage adjustments may be needed.
- Other Antihypertensives: Additive effects.
- Cholestyramine/Colestipol: Impairs absorption.
✔️ Contraindications
- Hypersensitivity to any components of the product.
- Anuria or hypersensitivity to sulfonamide-derived drugs.
✔️ Pregnancy & Lactation
- Pregnancy: Should not be used, especially in the 2nd and 3rd trimesters.
- Nursing Mothers: Valsartan's excretion in human milk is unknown; Hydrochlorothiazide is excreted in breast milk.
✔️ Precautions & Warnings
- Hepatic Function: Use caution in patients with mild to moderate hepatic impairment.
- Renal Function: Monitor renal function and adjust dosage as necessary.
- Heart Failure/Myocardial Infarction: Use caution when initiating therapy in these patients.
✔️ Storage Conditions:
Store between 15-30° C.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
